Film ini disutradarai oleh Peter Sohn, seperti yang diumumkan pada bukan Oktober 2014. Film ini menjadi film animasi Pixar kedua yang dirilis di tahun 2015 membuat Pixar bisa merilis dua film di tahun yang sama.
- Raymond Ochoa as Arlo, the youngest of the Apatosaurus family and the protagonist
- Jack Bright as Spot, a 6–7-year-old human caveboy that Arlo befriends.
- Sam Elliott as Butch, a Tyrannosaurus who runs a “ranch” filled with prehistoric longhorns.
- Anna Paquin as Ramsey, Butch’s daughter
- A. J. Buckley as Nash, Butch’s son
- Jeffrey Wright as Poppa Henry, the father of the Apatosaurus family.
- Frances McDormand as Momma Ida, the mother of the Apatosaurus family.
- Marcus Scribner as Buck, Arlo’s brother
- Ryan Teeple as Young Buck
- Maleah Padilla as Libby, Arlo’s sister[9]
- Steve Zahn as Thunderclap, a pterodactyl and the main antagonist
- Mandy Freund as Downpour, a pterodactyl
- Steven Clay Hunter as Coldfront, a pterodactyl
- Peter Sohn as Forrest Woodbush, a Styracosaurus who has various animals on his horns.
- Dave Boat as Bubbha, a Velociraptor rustler and the secondary antagonist.
- Carrie Paff as Lurleane, a Velociraptor who is a member of Bubbha’s pack.
- Calum Mackenzie Grant as Pervis, a Velociraptor who is a member of Bubbha’s pack.
- John Ratzenberger as Earl, a Velociraptor who is a member of Bubbha’s pack.